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Aesthetic injector placing Xeomin into a patient's brow area at The Spa by Sheena — physician-supervised med spa in Lubbock, TX

injectables

Xeomin

Xeomin is a purified "naked" neurotoxin — incobotulinumtoxinA by Merz — that softens frown lines, forehead lines, and crow's feet by relaxing the muscles underneath. At The Spa by Sheena in Lubbock, Xeomin is $14 per unit, injected by Becca (MSN, FNP-C) or Angie (RN). Results appear within a few days and last about 3 to 4 months.

3 to 4 months

Movement starts easing within a few days, the full effect lands around two weeks, and results last about 3 to 4 months before maintenance.

In-office injectable

A short series of small injections with a fine needle, about 15 minutes, with little to no downtime.

Upper face

Frown lines between the brows, horizontal forehead lines, and crow's feet at the corners of the eyes.

Softens expression lines

Softens the dynamic lines that form from repeated expressions such as frowning, raising the brows, and squinting; chosen by some patients for its accessory-protein-free ("naked toxin") formulation.

Purified neurotoxin (incobotulinumtoxinA)

What is Xeomin?

Xeomin is an FDA-approved wrinkle relaxer made by a German company called Merz. It's in the same family as Botox — same active ingredient, same mechanism, same 3 to 4 month duration, same 1:1 unit dose (a unit of Xeomin is priced and dosed just like a unit of Botox). But there's one important difference.

Xeomin is the "clean" wrinkle relaxer. It's filtered to remove the accessory proteins that come with Botox and Dysport, so what ends up in your face is just the active ingredient — nothing else. Merz built it this way for a reason.

Over time, some clients develop a mild immune response to those extra proteins. When that happens, their Botox stops working as well — the result fades faster, the softening isn't as complete, or a dose that used to be perfect suddenly feels light. Because Xeomin doesn't contain those extra proteins, it sidesteps the resistance problem entirely. In clinical use, Xeomin has a very low rate of antibody formation.

That's why we most often recommend Xeomin to clients who have been getting Botox for years and are starting to feel like it's not working as well as it used to. A switch to Xeomin often restores the full response.

Xeomin has been used clinically for over 15 years and FDA-approved in the U.S. for cosmetic use since 2011.

What to expect from your Xeomin appointment

Xeomin starts working in the same window as Botox — most clients see softening in 3 to 5 days, with full result by day 14. In head-to-head studies, Xeomin actually reached its peak effect faster than Botox (day 4 vs day 8) in some measures, though most clients experience them as similar.

After your appointment, keep it easy for 24 hours: stay upright for 4 hours, no makeup for 3 hours, no exercise or sweat for 12 hours, no flights for 48 hours. Little bumps at the injection sites are normal and gone within the hour. If you bruise, it clears in a week or so.

Duration is 3 to 4 months — same rhythm as Botox. Most clients rebook every 3 to 4 months. If you were coming in for Botox before and switched because it stopped working as well, you'll often find your Xeomin result feels closer to your original Botox response.

A gloved injector administers a neurotoxin injection to a reclining woman's forehead in a bright treatment room.

Benefits of Xeomin

NAKED FORMULA

Filtered to remove accessory proteins—the cleanest neurotoxin formulation available.

RESISTANCE OPTION

Excellent choice for patients who've developed reduced response to Botox or Dysport over years of treatment.

AUTOIMMUNE FRIENDLY

Patients with autoimmune sensitivities often prefer Xeomin's minimal formulation.

WRINKLE SOFTENING

Same effective wrinkle reduction as other neurotoxins with the cleanest possible formulation.

FDA-APPROVED

Long-established neurotoxin with consistent results and a strong safety profile.

A 15 to 20 minute visit with your injector

Inside a Xeomin appointment

Every Xeomin visit starts with a short consultation. Your injector watches how your face moves, asks about your health history and the medications you take, and maps where each unit goes. The product goes in with a very fine needle across a few small injections, and the appointment usually runs about 15 minutes. Your injector is Becca (MSN, FNP-C) or Angie (RN), both working under our medical director Dr. Arledge, a plastic surgeon. The Spa has been open in Lubbock since 2016.

You will not see a change the day of your appointment. Most people notice movement easing within a few days, with the full effect around two weeks in. It then wears off slowly, and most people come back for maintenance in about three to four months, which lines up with Botox. Xeomin is $14 per unit, billed by the unit rather than by the area, so your total depends on how many units your muscles need. We do not accept or bill insurance, and cosmetic neurotoxin is not covered anyway.

Side effects tend to be mild and short-lived. The most common one is a headache in the first day or two. You may also see minor redness, swelling, or a little bruising where the needle went in. A less common effect is a temporary droop of the eyelid or brow, which happens when a small amount of product settles into a nearby muscle; it fades on its own as the Xeomin wears off. We cannot promise a specific outcome, and results do vary from one person to the next.

Xeomin is not right for everyone. It should be avoided during pregnancy and breastfeeding, and it is not recommended if you have a neuromuscular condition such as myasthenia gravis, ALS, or Lambert-Eaton syndrome, since these can raise the risk of muscle weakness. Tell your injector if you take an aminoglycoside antibiotic, like gentamicin, because it can strengthen the toxin's effect. The best way to find out whether Xeomin fits you is to ask. Bring your questions to a consultation. Book online or call (806) 701-5840.

Onset, duration, and formulation — head to head

How Xeomin compares to Botox, Dysport, and Daxxify

Xeomin sits right next to Botox on our menu, and for good reason. Both are botulinum toxin type A, both quiet the muscle so the line above it softens, and both are $14 per unit here. The dosing runs close, too. Trials treating frown lines have used Xeomin and Botox at the same 20-unit dose and found the results hold up the same way, so your injector plans a similar number of units to what Botox would take. We still settle the exact number at your visit, once we see how your face moves.

The real difference is in the formula. Botox and Dysport carry the active toxin bundled together with accessory proteins left over from how the toxin is made. Xeomin is purified down to only the 150 kDa neurotoxin, with those complexing proteins stripped away. That is why people call it the "naked" toxin. Same active molecule, nothing riding along with it.

Some patients choose Xeomin for that reason. The thinking is that fewer added proteins may give the immune system less to react to over years of treatment, since the body can sometimes build antibodies that make a neurotoxin work less well. Studies have reported low rates of those antibodies with Xeomin. We want to be straight with you, though. That is a reason some people prefer it, not a promise that Xeomin prevents resistance or that it will work when another product has stopped. If it is on your mind, raise it at your consultation. It helps to know the rest of the menu too: Dysport and our other neurotoxins each have their own profile, and if your goal is added volume rather than softer lines, that is the job of dermal fillers instead.

PRICE RANGE

$14 / unit

PER SESSION

VIP members save 10% on every session

POST CARE 

View our post-care guide for important aftercare instructions to help support healing and maximize your results.

View Aftercare Guide

FAQ

Your questions,  answered

 We’ve answered some of the most common questions below to help make your experience simple, transparent, and stress-free.

Xeomin (incobotulinumtoxinA) is an FDA-approved neurotoxin that's been "naked"—the accessory proteins typically attached to botulinum toxin have been filtered out. Xeomin is just the pure neurotoxin molecule, nothing else. Same effectiveness as Botox; fewer additional proteins means lower theoretical risk of immune resistance over time.

What is Xeomin and how is it different from Botox?

Patients who've used Botox or Dysport for years and started seeing reduced effectiveness (possible immune resistance), patients with concerns about accessory proteins, and patients with autoimmune history who want the cleanest possible formulation. Most first-time patients don't need to start with Xeomin—but it's a great option if you've plateaued on other products.

Who should consider Xeomin?

Average 3–4 months, similar to Botox. Some research suggests slightly faster onset. Most patients see no clinical difference in duration compared to Botox or Dysport.

How long does Xeomin last?

Xeomin is $14 per unit—identical to Botox per-unit pricing. Unit counts and effect are also comparable. The reason to choose Xeomin isn't price; it's that Xeomin has no accessory proteins, useful for patients who've developed resistance to Botox or Dysport over years of treatment. Members receive discounted pricing on all neurotoxins.

Does Xeomin cost more than Botox?

Not for most patients—same effectiveness, same duration. "Better" depends on your situation. If you've developed resistance to Botox, Xeomin is better for you. If you've responded well to Botox for years, no reason to switch.

Is Xeomin better than Botox?

Same as other neurotoxins—quick pinches with an ultra-fine needle. Topical numbing available for sensitive patients.

Does Xeomin hurt?

Same as other neurotoxins. No real downtime, stay upright for 4 hours, avoid heat/strenuous exercise for 24 hours. Effects begin at 4–7 days, peak at 14 days.

What's the recovery from Xeomin?

Yes—straightforward switch with no waiting period needed. Many patients try Xeomin specifically because Botox stopped working as well. We can discuss whether switching makes sense for you at consultation.

Can I switch from Botox to Xeomin?

Theoretically less likely than other neurotoxins because there are no accessory proteins to trigger antibody response. Patients who've been on Botox/Dysport for years may not see resistance issues at all when switching to Xeomin.

Will I lose response to Xeomin over time?

First-time patients: complimentary consultation to discuss whether Xeomin makes sense for your situation. Returning patients: book directly. Call (806) 701-5840 or book online.

How do I book Xeomin?

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